It is considered that there are up to 80 morphological types of multipolar neurons in bodies of mammals and humans. These neurons are classified depending on the size and shape of nerve cell bodies, structural features and length of cell processes (stellate, fusiform, pyramidal, piriform, basket neurons, etc.).

Autonomic nervous system ganglia contain large multipolar neurons #1, #2 with cell bodies of irregular shape and with cell processes of various length: shorter processes #1, #2 establish neuronal connections inside the ganglia while longer processes also take part in the formation of connections within their ganglia or generate them at the outside via nerve fibers.

The cerebellar cortex has characteristic large piriform neurons (Purkinje cells) #1, #2 whose cell bodies form a single row inside the ganglion layer (Purkinje cell layer). A pear-shaped nerve cell body gives rise to 2-3 primary dendrites #1, #2, which are directed into the external, molecular layer. The primary dendrites then branch into terminal dendrites. An axon originates from the nerve cell body into the internal, granular cortical layer (deeper into the cerebellum) and white matter.

The cerebral cortex is marked by a presence of pyramidal neurons. Histological sections show that their cell bodies #1, #2 are triangular, while the vertex (which is opposite to the base) is directed to the external surface of the cortex. The middle of basal portion in the nerve cell body gives rise to an axon #1, #2, whereas a long apical dendrite branches off from the opposite vertex, and lateral dendrites #1, #2 do the same from the lateral legs.