The stages of thrombocytic lineage development are presented in Diagram of hematopoiesis

• are large polyploid (4n, 8n) cells of 30-40 μm
• have lobed nuclei
• accumulate azurophilic granules in a considerable cytoplasmic volume
• lose their mitotic potential, divide by endomitosis

• are 50-70 μm in size
• still divide by endomitosis
• contain large polyploid nuclei of many lobes (up to 64n)
• show basophilic staining of the perinuclear cytoplasmic space; the space contains a lot of azurophilic granules; peripheral portions of the cytoplasm are clearer
• form proplatelet pseudopods that penetrate into blood capillaries and then disintegrate into separate platelets

Promegakaryocyte q.v.. Megakaryocytes q.v. #1, #2, #3 (residual)